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. 2012 Jan 19;8(1):e1002361. doi: 10.1371/journal.pcbi.1002361

Table 1. Examples of feedback and regulation in LuxI/LuxR quorum-sensing systems.

System, function, and feedback architecture Ref.
Vibrio fischeri LuxI/LuxR: Bioluminescence 13,14
Sending LuxI synthesizes AHL 13
Receiving AHL binds LuxR, probably drives dimerization 12
Feedback luxI expression activated by LuxR-AHL 13
Regulation luxR expression catabolite-repressed via CRP 5
Agrobacterium tumefaciens TraI/TraR: Ti plasmid conjugation 15,16
Sending TraI synthesizes AHL 17
Receiving AHL reversibly binds TraR, drives dimerization 17
Feedback traI and traR expression activated by TraR-AHL 15
Regulation traR expression octopine-responsive 15
Pseudomonas aeruginosa LasI/LasR: Biofilm formation; virulence 18
Sending LasI synthesizes 3O-C12-HSL 18
Receiving 3O-C12-HSL reversibly binds LuxR, drives multimerization 19
Feedback lasI expression activated by LasR-3O-C12-HSL 20
Regulation lasR expression regulated by a two-component system 4
Pseudomonas aeruginosa RhlI/RhlR: Biofilm formation; virulence 18
Sending RhlI synthesizes C4-HSL 18
Receiving C4-HSL reversibly binds RhlR homodimer 21
Feedback rhlI expression activated by RhlR-C4-HSL 22
Regulation rhlR expression activated by LasR-3O-C12-HSL 21