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A. ChIP for the TFIIIC component, TFIIIC65, shows significant association with endogenous and transgene-5S rDNA (Tg5S rDNA). In all cases except Tg5S#5, p<0.05 (two tailed t-test), relative to the negative control, the Ascl2 promoter. Relationship between TFIIIC65 enrichment and nucleolar association (B), Tk mRNA levels (C), and Tg5S copy number (D).
