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. 2012 Jan 19;8(1):e1002316. doi: 10.1371/journal.pcbi.1002316

Figure 4. Effect of the donor age on cell senescence.

Figure 4

The value of the parameter Inline graphic obtained in Fig. 3 as a function of the age of the donor for MSC isolated from bone marrow from iliac crest (BM) and femoral head (HIP). The decrease of Inline graphic with age indicates that for older donors cell senescence occurs more rapidly. HIP-MSC show a larger value of Inline graphic than MSC-BM. We report our estimates for the parameter Inline graphic in the inset, showing values compatible with Inline graphic reported in Ref. (26) and no significant age dependence.