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. 2012 Jan 19;8(1):e1002464. doi: 10.1371/journal.pgen.1002464

Figure 6. RIC-7 promotes neuropeptide release.

Figure 6

YFP-tagged NLP-21 and INS-22 were expressed in cholinergic motor neurons using the unc-129 promoter. Representative images (A) and summary data (B) are shown for NLP-21 (top) and INS-22 (bottom) fluorescence in dorsal cord axons of the indicated genotypes. The number of animals analyzed is indicated for each genotype. (C–D) Representative images (C) and summary data (D) are shown for NLP-21 and INS-22 fluorescence in coelomocytes of the indicated genotypes. The number of animals analyzed is indicated for each genotype. Values that differ significantly from wild type (**, p<0.001, ***, p<0.0001 Students t-test) and from ric-7 mutants (#, p<0.01, ##, p<0.001, Students t-test) are indicated. Error bars indicate SEM. For rescue experiments, ric-7 transgenes are as follows: pan-neuron (snb-1 promoter), DA neuron (unc-129 promoter).