Table 1. Sigma factors and transcription factors associated with genes exhibiting low or high levels of expression noise.
Transcription factor | Number of target genes | Noise level | p-value (two-sided Wilcox rank test) |
MetJ | 10 | low | 0.0016 |
σ32 | 64 | low | 0.0052 |
CpxR | 18 | low | 0.011 |
ArgR | 16 | low | 0.017 |
NarP | 6 | high | 0.039 |
TrpR | 6 | high | 0.029 |
GadX | 10 | high | 0.027 |
Fnr | 71 | high | 0.015 |
Hns | 43 | high | 0.0099 |
GadW | 5 | high | 0.0089 |
NarL | 19 | high | 0.0086 |
IhfA/B | 48 | high | 0.007 |
σ38 | 85 | high | 6.7e-7 |
We analyzed all factors listed in RegulonDB that regulate five or more targets (6 sigma factors and 43 transcription factors in total). All factors with p-values less than 0.05 (uncorrected for multiple tests) are shown.