Table 3.
Compound/concentrationa (μg/kg lipids) | n (cases/subcohort) | IRR (95% CI) | ||||
---|---|---|---|---|---|---|
Model 1b | Model 2c | |||||
PCB-118 | ||||||
10–25 | 53/50 | 1.00 | 1.00 | |||
25–34 | 63/62 | 0.97 (0.57, 1.66) | 0.88 (0.50, 1.56) | |||
34–48 | 58/56 | 1.00 (0.59, 1.71) | 0.96 (0.55, 1.65) | |||
48–62 | 34/38 | 0.78 (0.42, 1.45) | 0.67 (0.34, 1.31) | |||
62–150 | 25/27 | 0.79 (0.40, 1.55) | 0.72 (0.36, 1.44) | |||
Linear estimate per IQRd | 233/233 | 0.92 (0.72, 1.17) | 0.88 (0.68, 1.14) | |||
PCB-156 | ||||||
13–28 | 62/53 | 1.00 | 1.00 | |||
28–34 | 51/63 | 0.56 (0.33, 0.96) | 0.59 (0.34, 1.02) | |||
34–41 | 54/59 | 0.64 (0.38, 1.09) | 0.68 (0.40, 1.16) | |||
41–50 | 45/35 | 0.83 (0.46, 1.50) | 0.94 (0.51, 1.75) | |||
50–88 | 23/26 | 0.57 (0.28, 1.15) | 0.66 (0.31, 1.37) | |||
Linear estimate per IQRd | 235/236 | 0.95 (0.75, 1.20) | 1.01 (0.79, 1.29) | |||
PCB-99 | ||||||
9–20 | 32/49 | 1.00 | 1.00 | |||
20–27 | 42/41 | 1.63 (0.88, 3.02) | 1.60 (0.85, 3.01) | |||
27–37 | 53/44 | 1.59 (0.87, 2.91) | 1.56 (0.84, 2.89) | |||
37–47 | 24/27 | 1.20 (0.58, 2.48) | 1.20 (0.58, 2.49) | |||
47–110 | 20/16 | 1.45 (0.61, 3.43) | 1.42 (0.59, 3.40) | |||
Linear estimate per IQRd | 171/177 | 1.10 (0.83, 1.44) | 1.09 (0.83, 1.43) | |||
PCB-138 | ||||||
29–100 | 53/49 | 1.00 | 1.00 | |||
100–140 | 44/69 | 0.66 (0.38, 1.13) | 0.66 (0.38, 1.14) | |||
140–180 | 74/63 | 1.05 (0.63, 1.75) | 1.04 (0.62, 1.74) | |||
180–230 | 41/34 | 1.25 (0.67, 2.31) | 1.25 (0.67, 2.33) | |||
230–380 | 26/28 | 0.68 (0.34, 1.34) | 0.68 (0.34, 1.36) | |||
Linear estimate per IQRd | 238/243 | 0.99 (0.78, 1.25) | 0.99 (0.78, 1.26) | |||
PCB-153 | ||||||
98–240 | 56/55 | 1.00 | 1.00 | |||
240–300 | 57/61 | 0.87 (0.52, 1.47) | 0.88 (0.52, 1.50) | |||
300–370 | 56/73 | 0.64 (0.38, 1.07) | 0.67 (0.40, 1.12) | |||
370–430 | 42/28 | 1.38 (0.75, 2.53) | 1.50 (0.81, 2.78) | |||
430–730 | 28/27 | 0.79 (0.39, 1.57) | 0.85 (0.42, 1.73) | |||
Linear estimate per IQRd | 239/244 | 0.94 (0.75, 1.19) | 0.97 (0.77, 1.23) | |||
PCB-170 | ||||||
37–87 | 57/61 | 1.00 | 1.00 | |||
87–100 | 47/41 | 1.09 (0.63, 1.89) | 1.19 (0.68, 2.09) | |||
100–130 | 69/78 | 0.79 (0.48, 1.30) | 0.93 (0.54, 1.59) | |||
130–150 | 42/32 | 1.16 (0.64, 2.08) | 1.46 (0.75, 2.83) | |||
150–230 | 23/31 | 0.64 (0.32, 1.29) | 0.80 (0.38, 1.69) | |||
Linear estimate per IQRd | 238/243 | 0.89 (0.68, 1.18) | 0.98 (0.72, 1.33) | |||
Compound/concentrationa (μg/kg lipids) | n (cases/subcohort) | IRR (95% CI) | ||||
Model 1b | Model 2c | |||||
PCB-180 | ||||||
71–170 | 53/60 | 1.00 | 1.00 | |||
170–200 | 55/52 | 0.94 (0.56, 1.67) | 1.03 (0.60, 1.77) | |||
200–240 | 61/54 | 1.04 (0.62, 1.83) | 1.19 (0.69, 2.05) | |||
240–290 | 49/48 | 0.98 (0.50, 1.59) | 1.09 (0.59, 2.01) | |||
290–480 | 21/31 | 0.54 (0.27, 1.08) | 0.69 (0.32, 1.46) | |||
Linear estimate per IQRd | 239/245 | 0.90 (0.75, 1.08) | 0.99 (0.77, 1.27) | |||
PCB-183 | ||||||
6–19 | 59/53 | 1.00 | 1.00 | |||
19–24 | 35/54 | 0.59 (0.34, 1.05) | 0.58 (0.32, 1.03) | |||
24–31 | 69/60 | 0.92 (0.55, 1.53) | 0.91 (0.54, 1.51) | |||
31–39 | 40/34 | 1.03 (0.56, 1.90) | 1.03 (0.56, 1.90) | |||
39–65 | 23/26 | 0.66 (0.33, 1.31) | 0.68 (0.34, 1.37) | |||
Linear estimate per IQRd | 226/227 | 0.87 (0.70, 1.08) | 0.88 (0.70, 1.10) | |||
PCB-187 | ||||||
17–46 | 61/58 | 1.00 | 1.00 | |||
46–56 | 49/62 | 0.68 (0.40, 1.15) | 0.69 (0.40, 1.17) | |||
56–68 | 62/60 | 0.90 (0.54, 1.51) | 0.97 (0.57, 1.64) | |||
68–84 | 44/33 | 1.12 (0.60, 2.07) | 1.30 (0.68, 2.47) | |||
84–140 | 22/27 | 0.62 (0.30, 1.27) | 0.69 (0.33, 1.44) | |||
Linear estimate per IQRd | 238/240 | 0.88 (0.71, 1.11) | 0.92 (0.73, 1.15) | |||
PCB-201 | ||||||
6–15 | 43/47 | 1.00 | 1.00 | |||
15–19 | 62/61 | 0.91 (0.52, 1.59) | 0.98 (0.56, 1.73) | |||
19–23 | 58/47 | 1.10 (0.62, 1.97) | 1.20 (0.66, 2.21) | |||
23–28 | 36/44 | 0.69 (0.37, 1.29) | 0.82 (0.41, 1.67) | |||
28–45 | 25/28 | 0.73 (0.34, 1.56) | 0.88 (0.38, 2.03) | |||
Linear estimate per IQRd | 224/227 | 0.85 (0.64, 1.13) | 0.93 (0.68, 1.28) | |||
ΣPCBe | ||||||
150–770 | 62/59 | 1.00 | 1.00 | |||
770–939 | 55/66 | 0.74 (0.45, 1.24) | 0.74 (0.44, 1.24) | |||
939–1,143 | 57/62 | 0.78 (0.47, 1.30) | 0.81 (0.48, 1.35) | |||
1,143–1,351 | 42/32 | 1.08 (0.59, 1.95) | 1.15 (0.63, 2.11) | |||
1,351–2,157 | 23/26 | 0.65 (0.32, 1.33) | 0.71 (0.34, 1.45) | |||
Linear estimate per IQRf | 239/245 | 0.95 (0.76, 1.19) | 0.99 (0.79, 1.25) | |||
ΣPCBimmuneg | ||||||
150–530 | 60/58 | 1.00 | 1.00 | |||
530–650 | 55/63 | 0.77 (0.46, 1.30) | 0.79 (0.47, 1.34) | |||
650–790 | 59/65 | 0.77 (0.47, 1.29) | 0.82 (0.49, 1.38) | |||
790–930 | 42/32 | 1.15 (0.64, 2.09) | 1.29 (0.70, 2.38) | |||
930–1,490 | 23/27 | 0.62 (0.31, 1.26) | 0.68 (0.33, 1.41) | |||
Linear estimate per IQRh | 239/245 | 0.95 (0.76, 1.18) | 0.99 (0.78, 1.24) |