Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Aug 3;119(12):1775–1780. doi: 10.1289/ehp.1103781

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, ?Reproduced with permission from Environmental Health Perspectives?); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.

PMC Copyright notice

Twelve-hour exposure to low concentrations of BPA stimulated proliferation of GC-1 cells through activation of the GPCR, PKG, and EFGR-ERK pathways, as determined by the MTT assay (A) and by [³H]-thymidine incorporation (B), as described in “Materials and Methods.” (C) Viability of cells exposed to 10^–9 M BPA for 12 hr with or without pretreatment with H89, KT5823, PD98059, NF449, PTX, PP2, or AG1478 (inhibitors of PKA, PKG, MAPK, Gαs, Gαi/ Gαq, Src, and EFGR, respectively). Values shown for A–C are the percentage change above the control (mean ± SE), with the control set as 1; results represent three independent experiments performed in triplicate. *p < 0.05, compared with control. **p < 0.05, compared with 10^–12, 10^–11, 10^–7, 10^–6, or 10^–5 M BPA. ^#p < 0.05, compared with 10^–9 M BPA alone.