Table 3.

Cytotoxicities of Quinoline and Pyrroloquinoline Ammosamide Analogues in Cancer Cell Lines at 10 μM Concentration

compd	Growth Percenta
	Meanb	lung HOP-62	colon HCT-116	CNS SF-539	melanoma UACC-62	ovarian OVCAR-3	renal SN12C	prostate DU-145	breast MCF7
2	101.07	96.95	101.05	88.22	100.09	115.24	98.89	114.59	98.04
10	105.27	108.99	108.20	117.31	101.70	106.32	102.78	108.11	105.75
11	104.88	104.53	100.36	99.06	97.93	109.55	99.49	108.85	100.27
12	104.38	109.87	98.84	104.82	102.96	110.07	102.63	105.75	97.23
13	109.97	112.21	103.44	109.23	112.51	124.69	109.64	112.18	100.11
14	103.06	103.41	104.18	107.48	108.54	120.20	109.00	124.60	89.58
15	104.52	114.23	104.18	100.61	109.82	115.27	113.39	138.91	78.61
30	103.35	105.32	107.00	104.34	90.84	108.21	101.49	97.82	96.11
31	104.17	113.20	103.06	97.49	101.93	103.52	107.48	104.81	95.79
32	108.57	118.26	102.47	101.43	110.63	126.09	106.07	127.34	122.71
34	105.39	110.60	104.56	106.99	96.96	123.43	102.66	112.19	94.99

^aGrowth percent relative to control (untreated cell cultures).

^bMean growth percent in the NCI panel of 60 human cancer cell lines.