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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Mol Cancer Res. 2011 Nov 15;10(1):25–33. doi: 10.1158/1541-7786.MCR-11-0456

Figure 5.

Figure 5

PELP1downregulation reduces the metastatic potential of ER-negative cells in vivo. A, whole animal imaging analysis of mice (n=10/group) treated with MDA-MB231 and MDA-MB231-PELP1shRNA. Both dorsal and ventral views are shown. B, Luciferase signals were quantitated by using the software Living Image 3.2. C, Number of tumor nodules in the lung was measured in the control and PELP1-shRNA treated mice groups (n=10/group). D, Bone loss was detected by X-ray imaging analysis and bone and tumor volumes in sections of tibiae were quantified with histomorphometry analysis as described in Materials and Methods.