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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Mol Cancer Res. 2011 Nov 7;10(1):34–39. doi: 10.1158/1541-7786.MCR-11-0450

Figure 4. The GAP and tensin-binding activities of DLC1 are required for rescuing shDLC1 cell migration defect.

Figure 4

(A) shDLC1 cells infected with adenoviruses carrying lacZ, DLC1-WT, DLC1-K714E, or DLC1-Y442F for 24h were then seeded (105 cells) for 16h transwell migration assays. (B) Protein lysates (20 ug) from infected shDLC1 cells were analyzed by immunoblotting with indicated antibodies. (C) Protein lysates (20 ug) from shDLC1 transfected with EGFR or MEK1 siRNAs were analyzed by immunoblotting with indicated antibodies.