Table 3.
Stage | MAF | GG | GT | TT | * p-value |
---|---|---|---|---|---|
GWAS (n = 2,647) | 0.081 | 23 ± 6 (n = 2234) | 25 ± 6 (n = 393) | 28 ± 8 (n = 20) | 3.63 × 10−13 |
Replication (n = 2,050) | 0.077 | 25 ± 6 (n = 1774) | 26 ± 6 (n = 263) | 24 ± 9 (n = 13) | 2.42 × 10−02 |
Combined (n = 4,697) | 0.079 | 24 ± 6 (n = 4008) | 25 ± 6 (n = 656) | 26 ± 9 (n = 33) | 1.90 × 10−11 |
Mean serum Cp levels as a function of genotype for rs13072552. Minor allele frequency (MAF).
p-values obtained using log transformed Cp values and after adjustment for age and gender.