Figure 5.

AlstR-mediated inhibition of GABAergic neurons increases excitatory population activity in a Dlx5/6-Cre: AlstR mouse slice. (A1–C1) Time series data of VSD imaging of photostimulation-evoked activity in S1 cortex, in normal ACSF, in the presence and after washout of AL, respectively. The site of photostimulation is in cortical layer 4. (A2–C2) The time course of VSD signal (in the percent change of pixel intensity [ΔI/I%]) from the ROI indicated by the small rectangle in the first image frame in (A1–C1), respectively.