Table 2.
Healing process of gastric artificial ulcers after endoscopic submucosal dissection
| Author | Year | Total cases | Drugs administration | Weeks |
Ulcer healing rate (%) |
Average ulcer size |
||
| 4 wk | 8 wk | Maximal diameter (mm) | Resected area (mm2) | |||||
| Kakushima et al[71] | 2004 | 70 | PPI + sucralfate | 8 | NA | 100 | 34.7 | NA |
| Lee et al[76] | 2004 | 26 | OPZ 20 mg | 1 | 12 | NA | NA | 503 |
| 34 | OPZ 20 mg | 4 | 15 | NA | NA | 575 | ||
| Yamaguchi et al[78] | 2005 | 29 | OPZ 20 mg | 8 | NA | NA | 27.8 | NA |
| 28 | Famotidine 40 mg | 8 | NA | NA | 22.4 | NA | ||
| Uedo et al[79] | 2007 | 73 | RPZ 20 mg | 8 | NA | 83 | 41 | NA |
| 70 | Cimetidinde 800 mg | 8 | NA | 89 | 40.5 | NA | ||
| Asakuma et al[80] | 2009 | 28 | RPZ 20 mg + ES 3.0 g | 8 | 40.7 | 96.3 | NA | 1306 |
| 28 | RPZ 20 mg | 8 | 11.5 | 76.9 | NA | 1274 | ||
| Kato et al[81] | 2010 | 31 | RPZ 10 mg + rebamipide 300 mg | 4 | 68 | NA | 35 | NA |
| 31 | RPZ 10 mg | 4 | 35 | NA | 31 | NA | ||
| Fujiwara et al[82] | 2011 | 30 | RPZ 20 mg + rebamipide 300 mg | 8 | NA | 86.7 | 41 | 1453 |
| 31 | RPZ 20 mg | 8 | NA | 54.8 | 42.8 | 1521 | ||
| Niimi et al[77] | 2011 | 55 | RPZ 10 mg | 2 | NA | 80.0 | 32.7 | NA |
NA: Not analyzed; PPI: Proton pump inhibitor; OPZ: Omeprazole; RPZ: Rabeprazole; ES: Ecabet sodium.