Table 1.

Intensity and distribution of CX₃CR1 in normal and malignant breast tissues

Tissues	0	0 to 1	1 to 2	2 to 3	Total
Normal	21 (45%)	19 (40%)	6 (13%)	1 (2%)	47
Malignant	43 (21%)	54 (27%)	53 (26%)	52 (26%)	202

Staining intensity was scored based on a scale in which negative specimens were graded (0) and strongly positive samples were graded (3). To evaluate distribution, tissues with complete lack of staining were scored as (0); tissues prevalently negative for CX₃CR1 displaying some areas of positive staining were scored as (0 to 1); tissues showing uniform staining for CX₃CR1 were scored as either (1 to 2) or (2 to 3), based on the intensity of the signal observed. The increase in CX₃CR1 expression observed in cancer samples as compared to normal samples resulted to be statistically significant with a P-value equal to 0.0016.