Table 3.

International prognostic scoring system (IPSS) for MDS⁴,⁵

Score	0	0.5	1	1.5	2
Prognostic variables
% bone marrow blasts	<5%	5%–10%		11%–19%	20%–30%*
Karyotype**	Good	Intermediate	Poor
Cytopenias***	0–1	2–3

Notes:

^*This group is recognized as AML in the WHO classification;

^**Karyotype: Good = normal, −Y, del (5q), del (20q); Poor = complex (≥3 abnormalities) or chromosome 7 anomalies; Intermediate = other abnormalities;

^***Cytopenias: Hgb <10 g/dL; Neutrophils <1.8 × 10⁹/L; Platelets <100 × 10⁹/L.

Abbreviations: MDS, myelodysplastic syndrome; AML, acute myeloid leukemia; WHO, world health organization.