Table 2.

Advantages of low-molecular-weight heparin over unfractionated heparin

Greater bioavailability Predictability and dose-dependent plasma level Less risk of bleeding Lower incidence of heparin-induced thrombocytopenia Lower risk of heparin-induced osteoporosis No need for laboratory monitoring Can be safely administered in outpatient Duration of anticoagulant effect is longer, permitting once- or twice-daily administration