Table 2.

Clinical implications of cardiac iron assessment by T2* magnetic resonance imaging

Cardiac T2* (ms)	Clinical implication
≥20	No significant cardiac iron loading; continue current chelation
10 to <20	Mild to moderate cardiac iron loading with increased risk of cardiac complications; consider intensification of chelation such as increased dosea and/or continuous infusion (for deferoxamine); combination therapy with deferiprone and deferoxamine if available
<10	Severe cardiac iron loading with high risk of cardiac complications; intensify chelation such as increased dosea and/or continuous infusion (for deferoxamine); combination therapy with deferiprone and deferoxamine if available

Note:

^aChelator dose should not exceed approved range (see Table 3).