Table 1.

Added or modified parameters and initial conditions of the model. Parameters required for the modelling of pH buffer behaviour are in the left column. Parameters required for the modelling of K⁺, Na⁺ and Ca²⁺ dynamics are given the right column. Antiporter parameters are in the bottom left column.

parameter	value	parameter	value
[HCO3−]	25 mM	kK	49 202 pA
[CO32−]	50 µM	kNa	5367.6 pA
[H2CO3]	1.5 µM	kCa	327.25 pA
[H+]	63.1 nM	kNaK	14.3383 pA
kf1	0.11 s−1	kNaCa	20.14 pA
kf2	1.00 × 104 s−1	[K]e	5.0 mM
kf3	1.03 × 104 s−1	[K]i	130 mM
kb1	183.33 s−1	[Na]e	140 mM
kb2	9508.7 M−1 s−1	[Na]i	19 mM
kb3	8.1616 × 1010 M−1 s−1	[Ca]e	2.0023 mM
Km	23 mM	[Ca]i	0.0006 mM
imax	10 pA	x0	0.0012
		h0	0.0401