Table 2.

SPECT MPI indications observed in the study: comparison of 2005 and 2009 AUC.

Indications	2005	2009
Detection of CAD:
(i) symptomatic, intermediate or high pretest probability,	A	A
(ii) asymptomatic, moderate Framingham Risk Score (FRS)*,	U	ECG interpret: I, not: U
(iii) asymptomatic, high FRS,	A	A
(iv) asymptomatic, low FRS or symptomatic, ECG interpretable and able to exercise,	I	I
After revascularization (PCI or CABG):
(i) symptomatic,	A	A
(ii) asymptomatic or symptomatic prior to CABG, ≥5 yrs after†,	A	A
(iii) asymptomatic or symptomatic prior to PCI, ≥2 yrs after.	U	U
Prior test results:
(i) asymptomatic or stable symptoms, abnormal catheterization or prior SPECT ≥2 yrs to evaluate worsening disease	A	U
Preoperative evaluation prior to intermediate-high risk noncardiac surgery:
(i) clinical risk factors and poor exercise tolerance (<4 METs),	A	A
(ii) no or minor risk factors, normal exercise tolerance (≥4 METs).	I	I
Unclassified indications:
(i) syncope,	—	Low risk: I, int-high: A
(ii) intermediate Duke treadmill score, low FRS,	—	—
(iii) new onset atrial fibrillation, moderate FRS,	—	U
(iv) asymptomatic, prior myocardial infarct of unknown age,	—	U
(v) symptoms unknown before PCI < 2 yrs ago,	—	—
(vi) known CAD; failed PCI,	—	U
(vii) normal SPECT MPI >2 yrs ago, moderate FRS.	—	U

*ATP III in 2009 AUC. ^†No symptoms prior to revascularization in 2009 AUC.