Figure 1.

Oral administration of BBR lowered fasting blood glucose levels in streptozotocin-induced diabetic rats. NC: normal control; DB: diabetic control; BBR: diabetic rats gavaged with 100 mg/kg/d of berberine chloride dissolved in 0.5% carboxymethyl cellulose. The DB and NC groups were gavaged with the control vehicle of 0.5% carboxymethyl cellulose. Values are means ± S.E.M. (at week 0, n = 10 for all groups; at week 7, n = 10, 8, and 7 for the NC, DB, and BBR, resp.). a, b, c Mean values with different letters were significantly different (P < 0.05).