Figure 3.

Histological analyses of bronchial and terminal bronchiolar epithelia of rtTA⁺ (A and F) and BiTg (B and G) mice receiving standard chow. CCSP, red; ACT, green. We also performed morphometric analyses of WT versus BiTg mice for nuclear mass (C and H), CCSP (D and I), and ACT (E and J). CCSP⁺ cells were decreased approximately twofold in bronchial epithelia (D), and approximately fivefold in terminal bronchiolar epithelia (I). No genotype-dependent differences were detected for DAPI or ACT. Significance was established at P ≤ 0.05.