Fig. 4.

Expression of cadms at 24 hours post-fertilization (hpf). In situ hybridization performed on 24 hpf whole-mount zebrafish embryos reveals that the six cadm genes are expressed throughout the central nervous system, in particular in the developing brain, the visual system and the spinal cord. A–C: Expression for cadm1a and 1b is in a rostrocaudal gradient (A,B), being undetectable caudal to the dashed lines. cadm2a expression decreases rostrally at 48 hpf and is lost by 72 hpf (insets in C).