Fig. 6.

Expression of cadms in the visual system. In situ hybridization staining in sections of retina at 48 hpf (A–F), 5 days postfertilization (dpf; G–L), and adult zebrafish (M–R). S and T show hematoxylin and eosin staining (H&E) of sections of adult and 5 dpf, respectively; the different layers of the retina are indicated: PE, pigment epithelium; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer. Asterisk in T denotes the location of the marginal zone. cadm1a is expressed in the dividing ganglion cells (arrows in A), while cadm4 is more strongly expressed in the mature cells of the GCL (arrows in F). Arrowheads in G and J reveal precursors at the margin of the outer nuclear layer (ONL). Scale bars = 50 µm in A–F, 50 µm in G–L,T.