Figure 2.

Ets-2 (A72/A72) mice exhibit decreased expression of Type I collagen and α-SMA in the lungs after treatment with bleomycin, compared with ets-2 (WT/WT) mice, indicative of decreased myofibroblasts. After treatment with bleomycin for 33 days, lungs from bleomycin-treated mice underwent immunohistochemical staining for α-SMA (A) or Type I collagen (C). The quantification of these results is shown in B and D, respectively. Data represent the mean ± SEM of at least three mice per condition.