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Whole-cell cAMP concentrations in human airway smooth muscle cells treated with 5.59 ng/ml PAHs in 10% DMSO for 24 hours, and then treated with the adenylyl cyclase activator forskolin (2 × 10−5 M) for 15 minutes before the determination of [cAMP]. The data represent cAMP in pmol/mg protein (n = 6 dishes/condition). *P = 0.01, versus control samples treated with 10% DMSO alone.
