Table 2.

Common Design Flaws in Self-Monitoring of Blood Glucose Trials

Subject selection: Low baseline A1C
Subjects not using SMBG data
• Not instructed on interpreting meaning of SMBG
• Not permitted to respond to SMBG results
HCPs not using SMBG data
• Lack of medication titration algorithms
Design issues
• Small sample size
• Crossover effect: same HCP caring for both groups