. 2012 Jan 20;7(1):e30565. doi: 10.1371/journal.pone.0030565

Table 1. Statistical analysis of genetic interaction between spir and tin, spir and Doc, spir and pnr, spir and CycA.

Genotype	Normal hearts	Mutant hearts	%	Genotype	Normal hearts	Mutant hearts	%
spir^2F/+; tin³⁴⁶/+	153	43^#	22%	spir^2F/+; Df(3L)DocA/+	217	23^#	10%
tin³⁴⁶/+	249	30	11%	Df(3L)DocA/+	249	14	5%
spir^2F/+	257	13	5%	spir^2F/+	257	13	5%
P value	P_tin<0.0001^**				P_Doc = 0.06^*
spir^2F/+; pnr^vx6/+	134	41^#	23%	spir^2F/+; CycA^C8LR1/+	76	43	36%
pnr^vx6/+	136	13	9%	CycA^C8LR1/+	297	10	3%
spir^2F/+	257	13	5%	spir^2F/+	257	13	5%
P value	P_pnr<0.0001^**				P_CycA<0.0001^**

**The χ² test reveals in all three groups that the proportion of mutant and normal embryos is statistically different for single heterozygous and double heterozygous embryos.

*The χ² statistic is not significant at the 0.05 level, but at the 0.1 level.

Mutant hearts in these double heterozygotes denote gap phenotype.