Table 1.
Demographic and personal characteristics among basal cell carcinoma cases and non-cases in the United States Radiologic Technologists study
| Without BCC, % (n=55,922) | With BCC, % (n= 2,291) | P-valuea | P for trendb | |
|---|---|---|---|---|
| Sex | ||||
| Male | 19.9 | 21.2 | 0.132 | |
| Female | 80.1 | 78.8 | ||
| Age at entry, mean(SD) | 47.4 (8.3) | 49.6 (9.4) | <.0001 | |
| Age category | ||||
| 0 to 39 | 18.3 | 14.8 | <.0001 | <.0001 |
| 40 to 49 | 50.4 | 43.3 | ||
| 50 to 59 | 22.5 | 26.5 | ||
| 60+ | 8.8 | 15.3 | ||
| Follow-up (person-yrs), mean (SD) | 8.9 (1.6) | 5.5 (2.6) | <.0001 | |
| Education | ||||
| Two-year rad tech program | 44.7 | 43.8 | 0.0947 | 0.0947 |
| College or grad school | 39.5 | 41.8 | ||
| Missing | 15.8 | 14.4 | ||
| Body Mass Index, (kg/m2) | ||||
| Underweight, <18.5 | 1.4 | 1.6 | <.0001 | <.0001 |
| Normal, 18.5–24.9 | 50.4 | 56.3 | ||
| Overweight, 25–29.9 | 30.2 | 28.1 | ||
| Obese, ≥30 | 16.1 | 12.2 | ||
| Missing | 1.9 | 1.9 | ||
| Smoking status | ||||
| Non-smokers | 54.6 | 54.3 | 0.0326 | 0.3747 |
| Former | 32.0 | 33.9 | ||
| Current | 12.7 | 11.1 | ||
| Unknown | 0.7 | 0.7 | ||
| Alcohol | ||||
| < 1 drink per week | 48.4 | 44.9 | 0.0007 | 0.0001 |
| 1–6 drinks per week | 25.8 | 27.1 | ||
| 7+ drinks per week | 8.2 | 9.9 | ||
| Missing | 17.65 | 18.07 | ||
| Eye color | ||||
| Blue/green/grey | 43.7 | 50.9 | <.0001 | <.0001 |
| Hazel | 14.2 | 14.2 | ||
| Brown | 26.2 | 20.5 | ||
| Missing/Other | 15.8 | 14.4 | ||
| Natural hair color at age 20 | ||||
| Red | 2.6 | 4.3 | <.0001 | <.0001 |
| Blonde | 15.3 | 19.8 | ||
| Brown | 78.0 | 72.0 | ||
| Black | 3.5 | 3.1 | ||
| Missing/Other | 0.7 | 0.8 | ||
| Complexion | ||||
| Fair | 47.8 | 57.8 | <.0001 | <.0001 |
| Medium | 49.6 | 40.7 | ||
| Dark | 2.0 | 0.8 | ||
| Unknown | 0.6 | 0.7 | ||
| Ever blistering sunburn | ||||
| Yes | 59.5 | 69.3 | <.0001 | |
| No | 39.9 | 30.2 | ||
| Unknown | 0.6 | 0.5 | ||
| Skin reaction to 30 minutes of strong sunlight | ||||
| Severe sunburn | 34.0 | 45.4 | <.0001 | <.0001 |
| Mild sunburn | 52.8 | 45.9 | ||
| Tanned, no sunburn | 11.4 | 7.0 | ||
| No change in skin color | 1.3 | 1.1 | ||
| Unknown | 0.6 | 0.7 | ||
| Average lifetime solar UV, quartilec | ||||
| Q1 (lowest) | 23.6 | 21.7 | 0.0006 | <.0001 |
| Q2 | 23.6 | 22.2 | ||
| Q3 | 23.6 | 23.9 | ||
| Q4 (highest) | 23.4 | 27.0 | ||
| Missing | 5.8 | 5.2 | ||
| Any NSAID | ||||
| No | 16.0 | 15.8 | 0.8471 | |
| Yes | 81.9 | 81.8 | ||
| Missing | 2.13 | 2.44 | ||
| Aspirin, days per month | ||||
| No | 50.3 | 49.3 | 0.2367 | 0.0497 |
| 0 to 4 | 29.1 | 28.7 | ||
| 5 to 14 | 8.2 | 7.9 | ||
| 15 to 21 | 2.6 | 2.9 | ||
| 22+ | 6.7 | 7.8 | ||
| Missing | 3.1 | 3.3 | ||
| Other NSAID, days per month | ||||
| No | 32.3 | 34.1 | 0.1153 | 0.5679 |
| 0 to 4 | 34.5 | 33.1 | ||
| 5 to 14 | 18.0 | 16.5 | ||
| 15 to 21 | 5.0 | 5.0 | ||
| 22+ | 7.8 | 8.4 | ||
| Missing | 2.5 | 2.9 | ||
| Any acetaminophen | ||||
| No | 34.0 | 34.0 | 0.9173 | |
| Yes | 63.6 | 63.4 | ||
| Missing | 2.5 | 2.6 | ||
| Acetaminophen, days per month | ||||
| No | 34.0 | 34.0 | 0.0125 | 0.5409 |
| 0 to 4 | 43.4 | 44.0 | ||
| 5 to 14 | 14.2 | 12.3 | ||
| 15 to 21 | 2.9 | 3.0 | ||
| 22+ | 3.1 | 4.1 | ||
| Missing | 2.5 | 2.6 |
Abbreviations: BCC, basal cell carcinoma; SD, standard deviation; BMI, body mass index; cGy, centi-Gray
a
Chi2 test for categorical variables and two sample t-test for continuous variables
b
P for trend using Cochran-Armitage test
c
Solar UV exposure quartile calculated from summer erythemal UV values weighted by time outdoors