Table 3.
Number of cases | Unadjusted HR (95% CI) | P for trend | Adjusteda HR (95% CI) | P for trend | |
---|---|---|---|---|---|
Any NSAID | |||||
No | 361 | ||||
Yes | 1874 | 1.07 (0.96, 1.20) | 1.04 (0.92, 1.16) | ||
Aspirin, days per month | |||||
No | 1130 | ||||
0 to 4 | 658 | 0.99 (0.90, 1.09) | 0.33 | 1.01 (0.91, 1.11) | 0.29 |
5 to 14 | 182 | 0.93 (0.79, 1.08) | 0.90 (0.77, 1.06) | ||
15 to 21 | 66 | 0.99 (0.77, 1.27) | 0.98 (0.76, 1.27) | ||
22+ | 179 | 0.93 (0.79, 1.10) | 0.93 (0.79, 1.10) | ||
Other NSAID, days per month | |||||
No | 782 | ||||
0 to 4 | 758 | 1.08 (0.97, 1.20) | 0.66 | 1.05 (0.94, 1.16) | 0.98 |
5 to 14 | 377 | 1.04 (0.91, 1.17) | 1.01 (0.89, 1.15) | ||
15 to 21 | 115 | 1.09 (0.90, 1.33) | 1.07 (0.87, 1.31) | ||
22+ | 193 | 1.01 (0.87, 1.19) | 0.99 (0.84, 1.16) | ||
Any acetaminophen | |||||
No | 779 | ||||
Yes | 1452 | 1.15 (1.1, 1.26) | 1.14 (1.04, 1.25) | ||
Acetaminophen, days per month | |||||
No | 779 | ||||
0 to 4 | 1009 | 1.18 (1.08, 1.30) | 0.03 | 1.18 (1.07, 1.30) | 0.08 |
5 to 14 | 281 | 1.01 (0.88, 1.16) | 1.00 (0.87, 1.16) | ||
15 to 21 | 69 | 1.17 (0.91, 1.50) | 1.19 (0.93, 1.52) | ||
22+ | 93 | 1.30 (1.05, 1.61) | 1.22 (0.98, 1.53) |
Adjusted for age, sex, solar UV exposure quartile calculated from summer erythemal UV values weighted by time outdoors
P for trend from treating categorical medication variable as continuous in regression