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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Neuropharmacology. 2011 Oct 31;62(2):1019–1027. doi: 10.1016/j.neuropharm.2011.10.011

Figure 4.

Figure 4

Effect of PMSF (900 nM) on anandamide and THC stimulated CB1 mediated G-protein activation (panel A). Whole brain levels of THC (ng, panel B), and anandamide (pmol/g, panel C) at 0, 30 and 120 min following 20 mg/kg i.p. injection of THC +/− 30 mg/kg PMSF . 0 time point indicates THC and anandamide levels in animals that received a PMSF injection, then a vehicle injection 20 min later, and then immediately euthanized. Asterisk (*) symbol indicates a significant difference compared to time 0 (panel B) or to vehicle treatment (panel C); i.e., main effect for time or pre-treatment, respectively.