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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Immunol. 2011 Dec 16;188(3):1381–1393. doi: 10.4049/jimmunol.1102359

Figure 7. Depletion of CD4+ T cells but not NK/ NKT cells reduces expression of interferon inducible transcripts.

Figure 7

Analysis of serum IFN-γ and interferon-inducible transcripts in joint tissue at 14 days of infection (N≥7). B6 IL-10−/− mice were injected with PBS, Mouse IgG2a (Isotype 1), α-NK1.1, Rat IgG2b (Isotype 2), or αCD4 during infection. ELISA analysis of serum IFN-γ (A). Expression of CXCL9 (B) and CXCL10 (C) in joint tissue was assessed by RT-PCR. Expression was normalized to β-actin. Statistical analysis was performed as described in Materials and Methods.