Table 3.
Multiple Linear Regression Models for Pulse Wave Velocity
Central PWV (hfPWV) (n=332) | Mixed Central/Peripheral PWV (baPWV) (n=334) | Peripheral PWV (faPWV) (n=319) | ||||
---|---|---|---|---|---|---|
Standardized Coefficient | p | Standardized Coefficient | p | Standardized Coefficient | p | |
R2 = 0.22 | R2 = 0.33 | R2 = 0.27 | ||||
Aldosterone | 0.10 | 0.049 | 0.07 | 0.12 | 0.08 | 0.13 |
Age | 0.35 | <0.0001 | 0.34 | <0.0001 | 0.16 | 0.001 |
Male Sex | 0.07 | 0.30 | 0.27 | <0.0001 | 0.29 | <0.0001 |
Black Race | 0.10 | 0.04 | 0.18 | <0.0001 | 0.13 | 0.01 |
Height | 0.12 | 0.09 | −0.20 | 0.002 | −0.42 | <0.0001 |
Waist Circumference | 0.07 | 0.30 | 0.09 | 0.13 | −0.02 | 0.77 |
MAP | 0.14 | 0.01 | 0.21 | <0.0001 | 0.28 | <0.0001 |
Heart Rate | 0.13 | 0.01 | 0.24 | <0.0001 | 0.13 | 0.01 |
R2 = 0.24 | R2 = 0.34 | R2 = 0.29 | ||||
Aldosterone | 0.08 | 0.10 | 0.06 | 0.22 | 0.06 | 0.23 |
Age | 0.35 | <0.0001 | 0.33 | <0.0001 | 0.20 | <0.0001 |
Male Sex | 0.11 | 0.12 | 0.30 | <0.0001 | 0.32 | <0.0001 |
Black Race | 0.10 | 0.05 | 0.18 | 0.0002 | 0.13 | 0.008 |
Height | 0.14 | 0.04 | −0.18 | 0.005 | −0.41 | <0.0001 |
Waist Circumference | 0.002 | 0.98 | 0.04 | 0.55 | −0.09 | 0.29 |
MAP | 0.12 | 0.008 | 0.22 | <0.0001 | 0.24 | <0.0001 |
Heart Rate | 0.12 | 0.02 | 0.23 | <0.0001 | 0.12 | 0.03 |
CRP | 0.14 | 0.02 | 0.12 | 0.02 | ||
HOMA-IR | 0.13 | 0.02 | ||||
Urinary Na/Cr | 0.08 | 0.12 |
Results are from ordinary least squares regression with the listed independent variables; CRP, aldosterone, urinary sodium/creatinine, HOMA-IR, and hfPWV are log transformed; R2 = model coefficient of determination; CRP=C-reactive protein, MAP=mean arterial pressure, HOMA-IR= homeostasis model assessment of insulin resistance, Urinary Na/Cr = 24-hour urinary sodium/creatinine ratio, hfPWV=heart-femoral pulse wave velocity, baPWV=brachial-ankle pulse wave velocity, faPWV=femoral-ankle pulse wave velocity