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Th1 polarization induced functional PSGL-1 expression. P-selectin–Ig binding (darker line/open shading) on CD4+ T cells before (unstimulated) and after in vitro polarization in either Th1 or Th17 conditions vs. chimeric control (lighter line/darker shading) showing functional PSGL-1 expression after Th1, but not Th17, polarization.
