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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Immunol. 2012 Jan 4;188(3):957–967. doi: 10.4049/jimmunol.1100461

Figure 2. SP-A enhances basal low level proliferation of T cell subsets in the lung in vivo.

Figure 2

Wild type or SP-A-/- mice were treated with i.p. BrdU and in drinking water over 4 d as described in Methods. Single cell preparations from the lungs were labeled with T cell markers to determine naïve, pre-activated, central memory or effector memory phenotypes (2A-D). All populations were concurrently analyzed for BrdU incorporation in the nucleus. Data is representative of 3 pooled samples from 3-4 mice in 3 independent experiments, and is depicted as mean fold difference normalized using the appropriate splenic T cell population as unity. *p<0.02, **p<0.01 compared to respective WT conditions.