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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Immunol. 2012 Jan 4;188(3):957–967. doi: 10.4049/jimmunol.1100461

Figure 3. Human T cells respond to SP-A in an integrated strength of signal dependent manner.

Figure 3

Purified human T cells from PBMCs were stimulated for a total of 75 h with either soluble anti-CD3 (sol aCD3: A and C) or plate-bound anti-CD3 (pb aCD3: B and D) in the absence or presence of anti-CD28. Control Ig or purified human SP-A (20 μg/ml) was added as indicated. Mean cpm of [3H]-thymidine incorporation over 15 h by proliferating cells from replicate wells in 9 individual subjects is depicted. Scales for mean cpm on the Y-axis expand with increasing levels of stimulation. p values from the Mann-Whitney test are as indicated in the plots.