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IL-17A knockout ameliorated myocardial I/R injury. A, Representative images of LV slices from wild-type and Il17a−/− mice at 1 day after I/R. B, Quantification of infarct size of myocardium 1 day after reperfusion (n=8). C, Representative M-mode images of the LV after sham and myocardial I/R from wild-type and Il17a−/− mice. D, Ejection fraction and LV fractional shortening (n=8). ** P<0.01 versus wild-type.
