Skip to main content
. Author manuscript; available in PMC: 2012 Jan 21.
Published in final edited form as: ChemMedChem. 2009 Oct;4(10):1615–1629. doi: 10.1002/cmdc.200900226

Scheme 3.

Scheme 3

Reagents and conditions: a) NaOH, EtOH, THF, H2O; b) HATU, DiPEA, DMF, CH2Cl2, cyclohexylamine for 26 a or piperidine for 26 b; c) K2CO3, [Pd(OAc)2], nBu4NCl, DMF, 1-naphthylboronic acid for 27 and 28 or 2-naphthylboronic acid for 29 or 4-chlorophenylboronic acid for 30 or 4-methoxyboronic acid for 31 or 4-pyridylboronic acid for 32.