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Effect of a 20-day period of topical treatment with ointment-based extract (5% and 20%) of Peganum harmala seeds on cutaneous leishmaniasis in outbred mice infected with Leishmania major. Lesion size in each test group is compared with those of control and placebo groups at the beginning of (week 0), just after (week 4) and 6 weeks after completion of (week 10) the treatment. The values represent the mean ± SEM. *p < 0.05; **p < 0.001
