Skip to main content
. Author manuscript; available in PMC: 2012 Mar 8.
Published in final edited form as: Nature. 2011 Aug 14;477(7363):229–233. doi: 10.1038/nature10329

Figure 1. TSLP promotes peripheral basophilia.

Figure 1

IL-4/eGFP reporter mice were treated with PBS or rTSLP and splenic basophils were (a) identified and (b) quantified. WT mice were treated with control-cDNA or TSLP-encoding (TSLP-cDNA) plasmid and splenic basophils were (c) identified and (d) quantified. Serum (e) IL-4, (f) IL-5, (g) IL-13 and (h) total IgE were quantified. (i), Histologic analysis of small intestine. Scale bars, 100 μm. (j), Splenic basophils from control mice (WT), or (SPC-TSLP) mice were identified (j) and (k) quantified. Results are representative of at least three (a-d and j-k) or two (e-i) separate experiments containing 3-5 (a-d), 5 (e-i) or 6-12 (j-k) mice per group. Statistical analyses performed using a two-tailed students t test (*, p<0.05), (**, p<0.01).