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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Wiley Interdiscip Rev RNA. 2011 Oct 19;3(2):286–293. doi: 10.1002/wrna.115

Figure 1.

Figure 1

Schematic diagram illustrates the model for sorting of cargo into MVB and fate of the exosomes. Sorting of exosomes followed by the biosynthetic pathway leads to miRNA processing, exocytosis, or back fusion with the plasma membrane/within an endosomal compartment or lysosomal degradation.