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Quantitative analysis of H and L chains from each B cell subset from glD42H mice and 50:50 wt/glD42H chimeric mice. Ratio of VκRF and glD42H to CD19 expression in B cell subsets. Negative selection of glD42H/VκRF-expressing B cells occurs at the T1 stage, and positive selection occurs at the GC stage. Pellets from three individual mice were used per group, and experiments were repeated once. *Not done, †p < 0.01, ‡p < 0.05 compared with previous B cell developmental stage.
