Table 1.

The Demographics and the Prevalent Diseases of the Enrolled Participants

Variable	Healthy Control N = 279	Control N = 280	HFPEF N = 175	HFREF N = 146	p-value	Pairwise comparison
Age (years)	78±6	76 ± 6	76 ± 5	77 ± 6	0.01	2*
Male n (%)	144 (51)	146 (52)	79 (45)	92 (63)	0.02	3*, 5*, 6*
White n(%)	269 (95)	154 (55)	149 (85)	128 (88)	<0.0001	1†, 2‡, 3‡, 4‡, 5‡
Diabetes n (%)	0	59 (21)	47 (27)	44 (30)	0.17	1‡, 2‡, 3†, 4*
Hypertension n (%)	3 (1)	160 (57)	93 (53)	70 (48)	0.0003	1‡, 2‡, 3‡, 4†, 5‡
Hyperlipidemia n (%)	127 (45)	148 (53)	84 (48)	61 (42)	0.11	NS
Stroke or TIA n (%)	0	36 (13)	37 (21)	42 (29)	0.001	1‡, 2‡, 3‡, 4*, 5‡
Myocardial Infarction n(%)	0	39 (14)	67 (38)	93 (64)	<0.0001	1‡, 2‡, 3‡, 4‡, 5‡, 6‡
Incidence rate of hospitalization for heart failure n (%)	-	-	131 (75)	128 (88)	<0.0001	N/A

1 indicates healthy control versus control; 2, healthy control versus DHF; 3, healthy control versus SHF; 4, control versus DHF; 5, control versus SHF; 6, DHD versus SHF.

^*P< 0.05;

^†P<0.01;

^‡P<0.001