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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Circ Heart Fail. 2011 Sep 7;4(6):733–739. doi: 10.1161/CIRCHEARTFAILURE.111.962027

Table 4.

The Association of Fibrosis Biomarkers with Cardiovascular Morbidity, All-cause and Cardiovascular Mortality for the Entire Cohort

Outcome Variable PIP
HR
(95%
CI)* 		PIP
HR
(95%
CI) † 		PIP
HR
(95%
CI)‡ 		CITP
HR
(95%
CI)* 		CITP
HR
(95%
CI)† 		CITP
HR
(95%
CI) ‡ 		PIIINP
HR
(95%
CI)* 		PIIINP
HR
(95%
CI)† 		PIIINP
HR
(95%
CI)‡
Myocardial
Infarction		 1.2
(0.8, 1.7)		 1.2
(0.8, 1.7)		 1.2
(0.8, 2.0)		 2.0
(1.2, 2.9) 		2.0
(1.2, 2.9) 		1.7
(1.2, 2.6) 		2.0
(1.4, 3.2) 		2.3
(1.4, 3.2) 		2.0
(1.4, 3.9)
Heart Failure§ 1.0
(0.6, 1.7)		 1.2
(1.0, 1.7)		 1.0
(0.6, 1.4)		 2.6
(1.4, 4.0) 		4.4
(3.2, 5.8) 		1.7
(1.2, 2.9) 		2.6
(1.7, 4.0) 		3.2
(2.6, 4.4) 		2.0
(1.2, 3.2)
Hospitalization
for HF 		1.2
(1.0, 1.7)		 1.2
(0.8, 1.4)		 1.2
(1.0, 1.7)		 2.9
(2.3, 3.6) 		2.6
(2.0, 3.6) 		2.3
(1.7, 3.2) 		2.9
(2.3, 3.6) 		2.6
(2.0, 3.6) 		2.6
(2.0, 3.6)
All-Cause Death 1.2
(1.0, 1.4)		 1.0
(0.8, 1.4)		 1.0
(0.8, 1.4)		 2.0
(1.7, 2.6) 		2.0
(1.4, 2.3) 		1.7
(1.4, 2.0) 		2.0
(1.4, 2.3) 		2.0
(1.4, 2.3) 		1.7
(1.4, 2.3)
Cardiovascular
Death		 1.2
(1.0, 1.7)		 1.2
(0.8, 1.7)		 1.2
(0.8, 1.7)		 2.0
(1.4, 2.9) 		2.0
(1.4, 2.6) 		1.4
(1.0, 2.0)		 1.7
(1.2, 2.3) 		1.7
(1.2, 2.3) 		1.4
(1.0, 2.0)
*

unadjusted

†

adjusted by age, gender and race

‡

adjusted by age, gender, race, hypertension, diabetes, hyperlipidemia

§

control and healthy control groups

pertains only to the HF groups