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Nuclear morphologic changes of K562 leukemia cells after different treatments for 48 hours: (A) untreated cells as control, (B) titanium dioxide nanoparticles, (C) daunorubicin alone, and (D) daunorubicin-titanium dioxide nanocomposites. Concentrations of daunorubicin and titanium dioxide nanoparticles are 0.5 μg/mL and 10 μg/mL, respectively.
Notes: Magnification: ×400. Arrows indicate cells with apoptotic nuclear condensation and fragmentation.
