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Representative micrographs of the surface of fibrinogen-coated polystyrene-coated quartz crystals as viewed by helium ion microscopy after the perfusion of platelet-rich plasma (A) and platelet-rich plasma in the presence of 10-nm silica nanoparticles (B) and 50-nm silica nanoparticles (C). Increased accumulation of platelet aggregates and bigger aggregates induced by the perfusion of platelet-rich plasma in the presence of silica nanoparticles is shown.
