Effects of silica, polystyrene, and gold nanoparticles on platelet receptors. (A) Representative flow cytometry recordings showing analysis of P-selectin on platelets in the presence and absence (resting) of 10-nm and 50-nm silica and polystyrene nanoparticles (up to 200 μg mL−1) and 18-nm gold nanoparticles (5 μg mL−1). Collagen (5 μg mL−1) was used as positive control. (B) Quantitative analysis of the effects of silica, polystyrene, and gold nanoparticles on P-selectin.
Notes: Data expressed as mean ± standard deviation. *P < 0.05; ***P < 0.001 versus resting.
Abbreviations: Au, gold; PS, polystyrene; SiO2, silica.