Table 2.
Adjusted odds ratios (aOR) for admission to hospital with asthma between 2 and 5 yrs of age (simultaneous adjustment for all listed factors in the entire table)
| aOR of asthma admission (95% CI) | |
|---|---|
| Maternal and environmental factors | |
| Maternal asthma admission* | 2.09 (1.90–2.29) |
| Maternal age <20 yrs | 1.20 (1.07–1.34) |
| Maternal age ≥35 yrs | 1.00 (0.94–1.07) |
| Nulliparous (first child) | 0.97 (0.92–1.02) |
| Smoked during pregnancy | 1.08 (1.02–1.15) |
| Urban area resident | 1.18 (1.10–1.26) |
| Most advantaged socio-economic quintile | 0.87 (0.80–0.95) |
| 2nd advantaged socio-economic quintile | 0.92 (0.86–0.99) |
| Pregnancy and delivery factors | |
| Spring conception | 1.03 (0.96–1.10) |
| Autumn conception | 1.09 (1.02–1.16) |
| Winter conception | 1.15 (1.08–1.23) |
| Antenatal admit UTI† | 1.49 (1.23–1.79) |
| Any maternal diabetes | 0.95 (0.86–1.06) |
| Any maternal hypertension | 1.02 (0.95–1.11) |
| Pre-term PROM‡ | 1.23 (1.04–1.45) |
| Term PROM‡ | 1.06 (0.97–1.16) |
| Induction with prostaglandins | 1.05 (0.97–1.13) |
| Cesarean section delivery | 1.03 (0.97–1.09) |
| Infant factors | |
| Male | 1.70 (1.62–1.79) |
| Gestational age (per additional week) | 0.947 (0.93–0.96) |
| SGA (<10th percentile size) | 1.08 (1.00–1.17) |
| LGA (>10th percentile size) | 0.97 (0.89–1.05) |
| Respiratory distress syndrome | 1.34 (1.12–1.60) |
| Transient tachypnea of newborn | 1.20 (1.07–1.36) |
| Jaundice and/or phototherapy | 1.10 (0.99–1.22) |
| Neonatal bacterial sepsis | 1.20 (0.90–1.60) |
LGA, large-for-gestational-age; PROM, pre-labor rupture of membranes; SGA, small-for-gestational-age.
*
Mother was admitted with asthma anytime between July 2000 and June 2009.
†
Urinary tract infection
‡
Spontaneous pre-labor rupture of membranes.