Figure 1.

The impact of miRNA research on clinical oncology. Alterations in miRNA expression are associated with pathophysiological changes in cancer cells. As miRNA signatures from cancer tissue or patients’ body fluids differ from those of healthy individuals miRNA signatures may likely to contribute to improved early diagnosis or patients’ prognosis. Through altered expression single miRNAs may act as oncogene or they may loose their tumor suppressor properties. Those miRNAs could be utilized for anti-cancer therapy.