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. 2012 Jan 1;2(1):76–85. doi: 10.7150/thno.3462

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Physicochemical parameters and comparison of magnetic properties. (A) A schematic representation of TCL-SPION and MION-47. (B) TEM image of TCL-SPION and MION-47. (C) A T₂-weighted MR image of TCL-SPION and MION-47 at various iron oxide concentrations. At identical iron oxide concentrations, TCL-SPION had a more intense MR contrast effect than MION-47. (D) Plots of the R₂(1/T₂) value. The relaxivity (R₂) of TCL-SPION (345.0 ± 6.2 mM^-1sec^-1, blue) was higher than that of MION-47 (130.7 ± 1.1 mM^-1sec^-1, red).