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. Author manuscript; available in PMC: 2013 Jan 2.
Published in final edited form as: FEBS Lett. 2011 Dec 9;586(1):102–106. doi: 10.1016/j.febslet.2011.12.005

Fig. 4. BaP induction of L1 promoter activity is ablated by HPV E7 viral oncoprotein.

Fig. 4

Transient transcription assays in HeLa cells with the pBASIC-luciferase (A), or the pL1Md-A5-luciferase (B), reporter vectors showing the effects of 0.06% DMSO or 3 μM BaP with or without HPV E7 oncoprotein forced overexpression. Cells were transfected for 6 hours, allowed to recover for 18 hours and chemically treated for 16 hours. Results are expressed as arbitrary luciferase units (ALU) and represent the mean ± S.D. of triplicate experiments after normalization to pRL. Statistic analyses were done using ANOVA (*, **, and *** indicate statistically significant differences, p<0.05, p<0.005 and p<0.0005 respectively). Each experiment was repeated at least 2 times.